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  • What is Cushing's syndrome?
  • Signs & Symptoms
  • Diagnosis
  • Treatment
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Frequently asked questions

Have more questions? Here are some of the most frequent queries we answer about your dog's condition:

Signs and Symptoms

What are the symptoms of Cushing’s syndrome?

The noticeable signs of Cushing’s syndrome are very similar to those associated with the ageing process, making it difficult to diagnose and later monitor.

The most noticeable signs of Cushing’s syndrome include;

  • Excessive urination with possible incontinence
  • Drinking more (excessive thirst)
  • Increased appetite
  • Excessive panting, even at rest
  • Muscle wastage and weakness
  • Lethargy
  • Urinary tract infections (cystitis)
  • Pot – belly
  • Patchy hair loss, recurrent skin infections
How is Cushing’s syndrome diagnosed?

When your veterinary surgeon suspects Cushing’s syndrome,  they will perform blood tests to confirm the diagnosis.

The cortisol concentration in the blood fluctuates greatly throughout the day in both healthy dogs and dogs with Cushing’s. It is for this reason diagnosis cannot be confirmed by just one measurement of cortisol. The two tests that are most commonly used to confirm a diagnosis of Cushing’s are called ACTH stimulation test and the low-dose dexamethasone suppression test. It may be necessary to perform both tests.

Vetoryl

Why do I have to give Vetoryl every day?

The active ingredient in Vetoryl is called trilostane. Trilostane is a short-acting medicine which needs to be given every day to control the disease.

How do I give Vetoryl to my dog?

It is recommended that you give your dog Vetoryl with a meal in the morning so that it can be easily absorbed; this also makes it easier for your veterinary surgeon to perform monitoring tests at the appropriate time after dosing.

What should I do if I forget to give a capsule?

Contact your veterinary surgeon. DO NOT give a double dose the next day.

Treatment

How long will my dog require treatment?

Most dogs will need Vetoryl every day for life. Cushing’s syndrome cannot be cured, but it can be successfully managed using Vetoryl.

How long will it take for my dog to improve on treatment?

The clinical signs of Cushing’s such as lethargy, increased drinking, eating and urination improve quickly, often within the first two weeks of treatment. Skin changes, hair loss and the pot belly can take up to 3 to 6 months to improve.

Track your dog's progress using your personalised treatment logbook.

Log in or sign up for your logbook here

Will I need to revisit my veterinary surgeon?

Yes. It is important that your dog revisits your veterinary surgeon for assessment and monitoring tests at 10 days, 4 weeks and 12 weeks after starting Vetoryl and thereafter every 3 months.

If your dog becomes unwell at any time whilst on Vetoryl, stop treatment and consult your veterinary surgeon as soon as possible.

Does Vetoryl have any side effects?

Vetoryl is well-tolerated by most dogs. If your dog develops any signs of illness whilst on Vetoryl including lethargy, vomiting, diarrhoea and anorexia stop treatment immediately and contact your veterinary surgeon as soon as possible.

 

If you become concerned with your dog's health
you should consult your veterinary surgeon immediately.

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Vetoryl

This site is provided as an information service for veterinary professionals and the owners of dogs who have been prescribed Vetoryl by their vet. Vetoryl is a prescription-only medicine, available only from your veterinary surgeon. Any questions about your dog should be directed to your veterinary practice. Vetoryl is a registered trademark of Dechra Limited.

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